See, someone started a NU Pokemon White Nuzlocke (but never finished it), so I'm thinking that, if I ever get to Nuzlocking RSE and a sane Ruby run bored me, I could always switch to Sapphire and use it as motivation to go do work as something less painful challenge myself by doing the same thing.

( Because all the pain is for pleasure/and nothing can measure... )
...Do note that Zigzagoon's evolution is NOT on this list. As such, I may or may not choose to use Dupes Clause in this hypothetical run.

Those that can be CAUGHT in RS:

( And good shall die first, said thy prophet,/ Our Lady of Pain. )
(list edited down from Moviebuff2287's Pokemon Locations FAQ)

In short, I would only get to use the following 34 Pokemon.
( these Pokemon may be bad, but they're perfectly good at it )

...In short, in a Dupes-Clause-Off run, I would live off of Pelipper, Wailord, Glalie, Seaking, Whiscash, Crawdaunt, a Wurmple evolution, Delcatty, Nosepass, Trapinch (UNEVOLVED), Masquerain, Spinda, Torkoal/Magcargo, Castform, Kecleon, Girafarig, Chimecho, and Relicanth. Any more team members would be sheer good fortune.

19 Pokemon, and all of them officially at the bottom of the barrel, competitive-play-wise. And almost all of them mortal bait for Wattson.

*in monotone voice* Oh, boy. This would be FUN.
[It's better than the FR/LG equivalent, though. Try using only Beedrill, Butterfree, Dewgong, Ditto, Farfetch'd, Lickitung, Parasect, Pidgeot, Raticate, Seaking, Venomoth, Wigglytuff to get you through the entire game... though I remember one crazy bastard solo'ing Emerald with a Rattata, so anything can be done, really.]

I'm not playing it NOW, obviously, since I have a lot to do. I just wanted to work out the practicalities, because I have a fondness for working out a lot of theoretical nonsense because I tend to either botch the application or wind up wanting to desperately do something else. Besides, it took my mind off... said stuff I have to do. :\